Description
Research Peptide≥99% HPLC StandardShips from Canada
Overview
Melanotan-2 is a synthetic cyclic analog of α-melanocyte-stimulating hormone (α-MSH) with broad, non-selective activity across melanocortin receptors, including MC1R and MC4R. It is supplied as a stable lyophilized peptide.
In research it is studied for two distinct melanocortin effects: pigmentation through MC1R and central effects on appetite and sexual behaviour through MC4R. It is offered strictly as a research material, and the study cited below describes clinical-pharmacology findings only.
Mechanisms of interest in research
Broad melanocortin-receptor agonism
Unlike MC1R-selective analogs, Melanotan-2 activates several melanocortin receptors. This lack of selectivity is the defining feature of its research profile, producing both pigmentary and central effects.
Pigmentation via MC1R
Through MC1R on melanocytes, Melanotan-2 stimulates eumelanin synthesis, studied in pigmentation models.
Central MC4R effects on appetite and sexual behaviour
Through MC4R in the hypothalamus, it is examined for effects on food intake and sexual-response pathways; its active metabolite in this context is the MC4R agonist bremelanotide.
Specifications
Selected Research
The following peer-reviewed studies are provided for scientific context on this compound’s research background. They describe preclinical and in-vitro findings only and are not claims about this product.
In a placebo-controlled study of 20 men with erectile dysfunction, Melanotan-2 produced penile erection in 17 of 20 men and increased sexual desire compared with placebo.
Wessells H, et al. Int J Impot Res. PMID: 11035391
This product is intended exclusively for in-vitro laboratory research. It is not a drug, food, dietary supplement, or cosmetic, and it is not intended for human or veterinary diagnostic, therapeutic, or recreational use.
